MKC-710D is a Karl Fischer moisture titrator (Coulometric titration)
developed to support DI (Data Integrity) based on GMP (Good Manufacturing Practice).
PRODUCT
Karl Fischer Moisture Titrator (Coulometric titration)
MKC-710D
Features
・Access Restrictions
Operators are authenticated to log on by an operator ID and password.
Only one operator can log on the system and operators can be changed via the logon/logoff function. Up to 100 operators can be registered, and an ID and password are registered for each operator.
Only one operator can log on even when 2 channels are connected.
An operator cannot log off during measurement.
・Rights Administration
You can assign the authorities to edit and set the functions to each operator.
There are five preset rights groups, and you can also create up to 10 rights groups arbitrarily according to the usage at your site.
Reliability improved by assigning each operator to a rights group.
・Electronic Approval / Electronic Signature
The electronic approval workflow consists of five stages: Check, Confirmation, and Approval, are in sequence, as well as denial, and unchecked status.
The signature level cannot be skipped, and always has to be signed in the Check, Confirmation, and Approval sequence.
A password is required when signing.
The signature details can be checked in the signature log.
Data integrity support functions without a PC
- Dl support function
Access Restrictions : Operator authentication by operator ID and password
Rights Administration : Each operator is assigned to a specific right group
Audit Trail : Operation histories are automatically recorded
Electronic Approval / Electronic Signature : Electronic approval and signature based on the workflow
Backup / Restoration : Automatic backup with the predetermined period
Archive / Archive View : Data storage. Archive data can be viewed on the main control unit
Data Capacity : The remaining capacity can be checked any time via an icon on the main screen
Security Settings : Password length and lockout settings can be set
LIMS Connection : Data output to LIMS systems
- The MKC-710D contains functions to support compliance with the following:
・European Pharmacopoeia Chapter 2.5.32. WATER: MICRO DETERMINATION: VERIFICATION OF ACCURACY
・Japanese Pharmacopoeia Eighteenth Edition Chapter 2.48: Water determination (Karl Fischer Method):
2.4 Suitability of determination
- Large color TFT-LCD with a touch panel (8.4-inch)
- The main control unit and a titrator are separately located by wireless (Bluetooth(R)).
- Measurement results can be saved in PDF files.
- The Water content can be displayed in real time.
- Energy saving designed.
- Maximum 2.6mgH2O/min of electrolysis speed.
Specifications
| Type | Karl Fischer Moisture Titrator |
|---|---|
| Model | MKC-710D |
| Standard configuration | MCU-710D+MKC-710+Manual Solvent Change unit |
| Measuring method | Water content : 1ug to 300mg (depends on reagent) Bromine index : 8ug to 300mg |
| Measurement cell | 2-Component or 1-Component |
| Precision | Relative standard deviation : less than 0.3% (n=10) *Per KEM standard measurement conditions and standard liquids |
| Display resolution | 0.1μg |
| Control method | Constant current pulse time control |
| Endpoint detection | Alternate current polarization method with a twin platinum electrode |
| EP sense method | Selective drift stability or limit measurement time |
| Required solvent | 2-Component cell : Anolyte 100mL , Catholyte 5mL 1-Component cell : Anolyte 150mL |
| Key operation | Touch panel |
| Displays | 1) 8.4-inch color LCD 800 x 600 dots 2) English / Japanese / Mandarin Chinese 3) Simultaneous 2-channel display |
| Calculation | Concentration of water content, statistics data processing (mean, SD and RSD) and automatic averaging of blank value and factor value |
| Data storage | Method: 120 (per channel) Measurement results: 5,000 samples (per channel) Operation history: 100,000 (Total for 2 channels) |
| DI support function | Access Restrictions: Operator authentication by operator ID and password Rights Administration: Each operator is assigned to a specific right Audit Trail: Operation history is automatically recorded Electronic Approval / Electronic Signature: Electronic approval and signature based on the workflow Backup / Restoration: Automatic backup with the predetermined period Archive / Archive View: Data storage. Archived data can be viewed on the main control unit Data Capacity: The remaining capacity can be checked any time via an icon on the main screen Security Setup: Password length and lockout settings can be set LIMS Connection: Data output to LIMS systems |
| External I/O | RS-232C port x4 : for Dot matrix printer , Electronic balance , Data Capture Software (SOFT-CAP) , Evaporator , Multiple sample changer USB ×1 : for USB flash drive , Thermal printer , A4 printer , Keyboard , Barcode reader , Foot switch , USB HUB LAN ×1 : for Personal computer (PC) |
| Extensibility | Measuring instrument : Karl Fischer Moisture Titrator (MKV-710/MKC-710) One of those instruments can be added Evaporator ADP-611 Multiple sample changer : CHK-501 |
| Ambient condition | 1) Temperature : 5 to 35°C 2) Humidity : 85%RH or below (no condensation) |
| Power source | AC100 to 240V +/- 10% 50/60 Hz |
| Dimensions | Touch panel controller : 225(W) x 190(D) x 42(H) mm Titration unit : 141(W) x 292(D) x 244(H) mm Stirrer : 107(W) x 206(D) x 340(H) mm (not incl. Solvent Change unit) Solvent Change Unit : 240(W) x 140(D) x 405(H) mm (not incl. tubing) |
| Weight | Touch panel controller : Approx.1.5kg Titration unit : Approx.3.0kg Stirrer : Approx.2.0kg Solvent Change Unit : Aprox.0.6kg |
| Conformity standard | CE marking EMC : EN61326-1 LVD : EN61010-1 |
Standards
ASTM D1123 Standard Test Methods for Water in Engine Coolant Concentrate by the Karl Fischer Reagent Method
ASTM D1533 Standard Test Method for Water in Insulating Liquids by Coulometric Karl Fischer Titration
ASTM D3401 Standard Test Methods for Water in Halogenated Organic Solvents and Their Admixtures
ASTM D4672 Standard Test Method for Polyurethane Raw Materials: Determination of Water Content of Polyols
ASTM D4928 Standard Test Method for Water in Crude Oils by Coulometric Karl Fischer Titration
ASTM D5460 Standard Test Method for Rubber Compounding Materials—Water in Rubber Additives
ASTM D6304 Standard Test Method for Determination of Water in Petroleum Products, Lubricating Oils, and Additives by Coulometric Karl Fischer Titration
ASTM D6869 Standard Test Method for Coulometric and Volumetric Determination of Moisture in Plastics Using the Karl Fischer Reaction (the Reaction of Iodine with Water)
ASTM E1064 Standard Test Method for Water in Organic Liquids by Coulometric Karl Fischer Titration
European Pharmacopoeia / 2.5.32. WATER: MICRO DETERMINATION
ISO 10101-3 Natural gas -- Determination of water by the Karl Fischer method -- Part 3: Coulometric procedure
ISO 12937 Petroleum products -- Determination of water -- Coulometric Karl Fischer titration method
ISO 14897 Plastics -- Polyols for use in the production of polyurethane -- Determination of water content
ISO 15512 Plastics -- Determination of water content
ISO 760 Determination of water -- Karl Fischer method (General method)
JIS C2101 Testing methods of electrical insulating oils
JIS K0068 Test methods for water content of chemical products
JIS K0113 General rules for methods of potentiometric, amperometric, coulometric, and Karl Fischer titrations
JIS K1557-2 Plastics -- Polyols for use in the production of polyurethane -- Part 2: Determination of water content
JIS K2275-3 Crude petroleum and petroleum products -- Determination of water -- Part 3: Coulometric Karl Fischer titration method
JIS M8211 Iron ores -- Method for determination of combined water content
JIS M8250 Iron ores -- Determination of hygroscopic moisture in analytical samples -- Gravimetric, Karl Fischer titration and mass-loss methods
United States Pharmacopeia–National Formulary / 38 <921> WATER: DETERMINATION
Software
Option
-
KEM Aqua Karl Fischer Reagents
“KEMAQUA Series"
Karl Fischer Reagent “KEMAQUA Series" is a reagent made by Kyoto Electronics Manufacturing for use with Karl Fischer Moisture titrator. It is available for a wide range of samples.
-
Evaporator
ADP-611
Drying oven for moisture measurement on chip, particulate or powder samples such as plastic pellets
Maximum set temperature : 300℃ -
Evaporator for High Temperature
ADP-512S
This oven evaporates moisture in ores, metallic powder, ceramics and other solids and powder materials by high heat (maximum: 1000℃) for measurement of water content connected to Karl Fischer moisture titrator.
-
Evaporator for Ores
ADP-512
This oven is designed to use with KEM Karl Fischer moisture titrator for measurement of combined water in iron ores according to JIS M8211 Iron Ores – Method for Determination of Combined Water Content.
-
Evaporator for Oil Samples
ADP-513
This unit evaporates moisture of samples dissolved in a heated base oil.
This unit is primarily used for moisture measurements in lubricant oil, grease, tar products, paints and other viscous liquids. -
Multiple Sample Changer for Coulometric Karl Fischer Moisture Titrators
CHK-501
Multiple sample evaporator for Coulometric Karl Fischer Moisture Titrators, suitable for the continuous measurement of up to 24 samples.
The heating temperature can be set for each sample individually, different kinds of sample can thus be measured automatically one after the other. An auto power off function after measurement ensures safe operation. -
Sampler
Sampler
-
Titration Vessel
Titration Vessel
-
1 Component Inner Burette
1 Component Inner Burette
Catalog
■General-Catalog.pdf
■Karl Fischer Moisture Titrator (DI support model) MKV-710D MKC-710D.pdf
